clinical features

Last reviewed 01/2018

Most infections are either mild or asymptomatic. In these patients an increase in peripheral blood eosinophil count is the only sign of infection (1).

skin manifestations

  • ground itch 
    • characteristic cutaneous reaction following acute larvae invasion of the skin
    • most commonly affects the foot
    • may cause serpiginous or urticarial tracts with severe pruritus lasting for several days

    Note: this should be differentiated form from cutaneous larva migrans

  •  larva currens (literally “running larvae”)
    • intensely itchy red tracts seen in the perianal area and upper thighs due to rapid speed of intradermal migration (progressing at around 5-15 cm per hour) of the parasite  in chronic infection
    •  pathognomonic for strongyloidiasis

pulmonary manifestations

  • dry cough or wheeze
  • Loeffler’s-like syndrome
    • rare
    • characterised by fever, dyspnoea, wheeze, pulmonary infiltrates on chest radiographs, and accompanying blood eosinophilia

gastrointestinal manifestations

  • diarrhoea, anorexia, and vomiting
  • epigastric pain worsened by eating (2)

Disseminated strongyloidiasis seen in immunosuppressed patients may present with

  • abdominal pain and distension
  • shock
  • pulmonary and neurologic complications
  • septicemia (2)

Reference: