immune phase

Last reviewed 01/2018

During the immune phase of leptospirosis about 50% of patients develop meningism, of whom about 33% have CSF lymphocytosis and raised protein in the CSF.

Generally the patients then make an uneventful recovery.

A minority of patients go on to develop:

• tender hepatomegaly
• jaundice
• haemolytic anaemia
• oliguric renal failure with microscopic haematuria
• sometimes cardiac involvement with atrial and ventricular dysrhythmias and congestive heart failure