cautions and side-effects

Last reviewed 01/2018

Cautions:

  • hepatic and renal impairment
  • elderly, young adults, and children
  • may mask underlying disorders eg cerebral irritation
  • avoid for 3-4 days after gastro-intestinal surgery
  • acute hypertensive response in phaeochromocytoma
  • pregnancy and breast-feeding
  • porphyria

Side-effects:

  • extrapyramidal effects (esp children/young adults)
  • hyperprolactinaemia
  • occasionally tardive dyskinesia if prolonged use
  • also reported: drowsiness, restlessness, diarrhoea, depression, neuroleptic malignant syndrome; cardiac conduction abnormalities with i.v. administration