stem-cell transplantation in severe systemic SLE

Last reviewed 01/2018

Patients with multiorgan SLE who do not respond to cyclophosphamide treatment have a high mortality.

Seven patients with severe SLE who had not responded to standard treatment with cyclophosphamide were treated with high dose chemotherapy and stem-cell transplantation.

Reference:

• 1) Traynor, AE, Schroeder, J. et al. (2000). Treatment of severe systemic lupus erythematosus with high-dose chemotherapy and haemopoietic stem-cell transplantation: a phase I study. Lancet 356; 701-07.