pathology

Last reviewed 01/2018

The following histological features are found irrespective of the cause of the chronic active hepatitis:

• intense portal inflammatory infiltrate which spills over into the liver parenchyma
• piecemeal hepatocyte necrosis
• bridging necrosis between adjacent triads
• progressive fibrosis beginning in the portal triads and radiating into the liver parenchyma
• the end-point is frank cirrhosis