localisation of cerebellar lesions

Last reviewed 01/2018

Cerebellar disease may be the result of lesions which affect:

• the cerebellum
• the input from proprioceptors, inner ear and cerebral hemispheres
• the output from the cerebellum, which passes via the superior cerebellar peduncles

The clinical features of lesions in different locations is outlined below:

Midline cerebellar lesions affect:

• anti-gravity reflexes
• gait and stance ataxia
• little limb ataxia

Lesions in the superior cerebellar peduncle (outflow lesions) cause:

• intention tremor

Lesions in the midbrain, pons and medulla (inflow & outflow lesions) cause:

• ataxia and/or intention tremor
• other localising brainstem signs e.g. cranial nerve palsies

Ref: Essential Neurology, Wilkinson, I.M.S., 1993, 2nd edition, Blackwell Scientific Publications, p.114