scleroderma sine scleroderma

Last reviewed 12/2022

This is an unusual form of systemic sclerosis which is characterised by:

• Raynaud's phenomenon
• pulmonary fibrosis
• renal failure
• cardiac fibrosis
• gastrointestinal fibrosis

There is little skin involvement.

Immunological investigation may reveal:

• anti-Scl 70 antibody
• anti-centromere antibody
• anti-nucleolus antibody