features and management
Last reviewed 01/2018
Clinical features:
- epigastric discomfort and nausea
Endoscopic features:
- may be no abnormality visible at gastroscopy; in general, erythema and erosions in the antral mucosa. If there is associated duodenitis then this increases the likelihood of H. pylori.
Diagnosis:
- listed separately
Management:
- NICE guidance states that H. pylori-positive peptic ulcer disease or non-ulcer dyspepsia requires treatment with H. pylori eradication therapy. For more detailed regarding the NICE guideline see linked item
Prognosis:
- natural history is uncertain. Often progresses to patchy atrophy (does not usually lead to complete achlorhydria). There is thought to be a 3-4 fold increased risk of gastric carcinoma. There is evidence linking this form of gastritis with the development of lymphoma of mucosa-associated lymphoid tissue type
Reference:
- NICE (September 2014).Dyspepsia and gastro-oesophageal reflux disease - Investigation and management of dyspepsia, symptoms suggestive of gastro-oesophageal reflux disease, or both
- Yeomans ND.Gastritis. Medicine International 1994; 22(6):221-4.
- Bayerdorffer E et al. Lancet 1995;345: 1591-3.
Helicobacter pylori triple therapy
NICE guidance - management of dyspepsia in adults in primary care (summary section)