reversible vs irreversible injury

Last reviewed 01/2018

There remains some debate as to whether increased levels of troponin T or I represent reversible or irreversible cardiac injury. Available clinical and experimental data suggests that troponin release represents irreversible injury.

From a pragmatic perspective, it also appears that prognosis is independently related to troponin elevation and it may not be clinically relevant to distinguish the whether the mechanism by which the cardiac injury has occurred is reversible or not.