common infections in hypogammaglobulinaemia
Last reviewed 01/2018
Infections in patients with hypogammaglobulinaemia tend to run a much more severe course.
- enterovirus infection may cause:
- meningitis
- convulsions
- VIIth nerve palsy
- deafness
- weight loss
- headache
- non-pitting oedema of the lower limb
- myositis
- progression over several years
- may cause death due to brain stem damage
- mycoplasmas - commonly causes septic arthritis
- bacteria:
- Haemophilus influenzae pneumonia is the commonest infection, often preceded by a viral upper respiratory tract infection
- repeated infection may cause bronchiectasis and cor pulmonale
- pneumococcal meningitis and pneumonia
- in young patients there may be pyoderma or septic arthritis due to Staphylococcal infection
- protozoans:
- Giardia lamblia