hyperpigmentation not due to melanin
Last reviewed 01/2018
Causes include:
- jaundice
- haemosiderosis
- carotenaemia
- alkaptonuria
- drugs:
- gold (blue/grey pigmentation on light-exposed skin)
- amiodarone (slatey grey pigmentation on light exposed skin)
- antimalarials (generalized diffuse grey/brown pigmentation; mepacrine causes discoloration that resembles jaundice, chloroquine use may cause bleaching of hair)
- minocycline
- oral contraceptive pill (brownish pigmentation on the face)
- phenytoin (brownish pigmentation on face)
- exogenous pigment:
- tattoos
- iodine
- potassium permanganate