persistent hyperinsulinaemic hypoglycaemia of infancy

Last reviewed 01/2018

Persistent hyperinsulinaemic hypoglycaemia of infancy (PHHI) is characterised by:

  • unregulated hyperinsulinaemia
  • severe hypoglycaemia and hypoketosis

Hypoglycaemia usually begins at birth. Many infants suffer brain damage from severe hypoglycaemia before the diagnosis is made.