diagnosis

Last reviewed 01/2018

The clinical features of aplastic anaemia are non-specific. Diagnosis is based upon:

• peripheral blood:
• neutrophils less than 0.5 x 10^9 per litre
• platelets less than 20 x 10^9 per litre
• reticulocyte count corrected for haematocrit less than 1%
• marrow:
• severe hypocellularity
• moderate hypocellularity with < 30% of residual cells being haematopoietic

At least two peripheral plus one marrow criteria must be satisfied.