investigations
Last reviewed 01/2018
The laboratory results show:
- low serum calcium
- increased plasma phosphate - low in hypocalcaemia due to intestinal malabsorption or vitamin D deficiency
- normal alkaline phosphatase - raised in hypocalcaemia due to chronic renal failure
- skull radiology may reveal basal ganglia calcification
- high PTH concentrations
- in type I pseudohypoparathyroidism, urinary cAMP fails to rise following administration of PTH
- in type II pseudohypoparathyroidism, urinary cAMP rises normally following PTH administration