thiazide in heart failure

Last reviewed 01/2018

  • may be used as initial treatment in heart failure e.g. cyclopenthiazide 0.25-0.5 mg/24h PO

The ALLHAT data revealed that chlorthalidone was superior to calcium channel blockers and, at least in the short term, angiotensin-converting enzyme inhibitors in preventing heart failure in hypertensive individuals.

Reference:

  1. Davis BR et al. Role of diuretics in the prevention of heart failure: the Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial. Circulation. 2006 May 9;113(18):2201-10