laboratory features of myeloproliferative disease

Last reviewed 05/2021

• chronic myeloid leukaemia: WBC (++), haematocrit (N), platelets (N or +), red cell morphology (N)

• myelofibrosis: WBC (N or + or -), haematocrit (N or -), platelets (N or + or -), red cell morphology (abnormal)

• polycythaemia vera: WBC (N or +), haematocrit (+), platelets (N or +), red cell morphology (N)

• essential thrombocythaemia: WBC (N or +), haematocrit (N), platelets (++), red cell morphology (N)

N.B. CML has Ph chromosome in 95% of cases + low LAP

• key: N = normal, + = increase, - = reduction