clinical features

Last reviewed 01/2018

The characteristics of William's syndrome are:

• supravalvular aortic stenosis
• elfin facies:
• small upturned nose
• large ridged teeth
• prominent jaw
• supraorbital ridges
• children fail to thrive and experience particular difficulties with language
• mild mental retardation; IQ from 20 to 106, with a mean of 58
• infantile hypercalcaemia
• exuberant personality - cocktail party chatter
• premature ageing of the skin