Frohlich's adiposogenital syndrome

Last reviewed 01/2018

Frohlich's adiposogenital syndrome seen in boys and is characterized by obesity and hypogonadotropic hypogonadism. There is delayed skeletal maturation.

Variable features in this syndrome include:

• diabetes insipidus
• visual impairment
• mental retardation

Patients with this condition may present with a slipped upper femoral epiphysis. They are likely to be fat and short.

The anterior pituitary is usually unaffected in these patients. The syndrome is believed to be a result of hypothalamic dysfunction.