long term
Last reviewed 01/2018
Long term drug side effects include:
- adaptive changes: - beta-blockers and upregulation of beta adrenoceptors during therapy - tardive dyskinesia and dopamine antagonists
- rebound phenomena: - sudden withdrawal - again, seen with beta blockers and corticosteroids - need to withdraw drug very slowly - 1mg at a time, once a month
- other: - chloroquine in the retina, amiodarone and deposition of phospholipids in tissues