Berger's disease
Last reviewed 01/2018
This is a glomerulopathy that is present in 50% of children with recurrent episodes of macroscopic haematuria. It also occurs in young adults. It is more common in males.
Episodes of haematuria are often simultaneous with periods of viral infection and flank pain.
Histology reveals a focal proliferative glomerulonephritis with IgA, and in some cases IgG, C3 and properdin deposits in the mesangium.
It is very unusual for a child with this condition to go on to develop chronic renal failure. However chronic renal failure is more common in adults.