propylthiouracil
Last reviewed 01/2018
This antithyroid drug inhibits the synthesis of thyroid hormone by inhibiting the organification of iodide. Additionally, it blocks the peripheral conversion of T4 to T3.
The half-life of propylthiouracil is one to two hours.
Its main use is the long term treatment of hyperthyroidism.
carbimazole / propylthioruacil in thyrotoxicosis