laboratory features

Last reviewed 01/2018

Micrangiopathic haemolytic anaemia is characterised by:

  • fragmented red blood cells - schistocytes, helmet cells, triangle forms - in peripheral blood smear
  • normocytic, normochromic
  • Hb usually < 10 gm/dl
  • marked reticulocytosis; occasionally, nucleated RBC's
  • haemolysis - increased serum indirect bilirubin, LDH, and serum haemoglobin; absent haptoglobin
  • negative Coomb's test