management of extrahepatic cholestasis
Last reviewed 01/2018
The management of extrahepatic cholestasis depends on the cause.
There are three general risks when operating on a patient with extra-hepatic cholestasis:
- hypocoagulability:
- due to prothrombin deficiency
- may be corrected by vitamin K administration
- postoperative renal failure:
- due to nephrotoxic effects of bile pigments and bowel toxins which escape hepatic detoxification
- may be prevented with intra- and post-operative use of diuretics e.g. frusemide
- sepsis:
- the combination of biliary sepsis and renal failure is usually fatal
- is prevented with prophylactic antibiotics
treatment of choledocholithiasis
dilatation of biliary stricture