clinical pharmacokinetics

Last reviewed 01/2023

Points of note about the pharmacokinetics of Gabapentin:

• it does not induce liver enzymes
• it does not bind to plasma proteins
• half-life is 5-7 hours
• dose should be adjusted on the basis of clinical symptoms and signs as well as seizure response
• it does not interact with other antiepileptic drugs or reduce the efficacy of oral contraceptives