management
Last reviewed 08/2021
Treatment with high dose corticosteroids (prednisolone 125mg on alternate days for eight weeks) has been shown to reduce the risk of significant renal failure. However the result was not confirmed in a MRC trial with a similar protocol.
Treatment with steroids and chlorambucil may be of help; but nephrologists have been reluctant to use this protocol soon after the onset of disease because of the risk of long-term complications in a treatment group where a large proportion of patients will go into spontaneous remission.
Symptomatic treatment of the nephrotic syndrome e.g. low salt diet, cautious use of diuretics.