adverse effects of neuroleptics

Last reviewed 01/2018

The adverse effects of neuroleptics include:

• anti-adrenergic effects:
• postural hypotension with reflex tachycardia - especially after i.m. injection
• nasal congestion
• inhibition of ejaculation

• anti-cholinergic:
• blurred vision
• dry mouth
• urinary retention
• constipation
• precipitation of glaucoma
• dry skin - danger of hyperthermia in very hot climates
• tachycardia

• neuroleptic-induced movement disorders

• psychiatric:
• restlessness and agitation
• depression, which may respond to antidepressants

• epileptogenic:
• especially chlorpromazine
• Pimozide is the safest

• neuroleptic malignant syndrome

• miscellaneous side-effects