SIADH

Last reviewed 07/2022

This is one of the most common causes of hyponatraemia; patients produce an inappropriately concentrated urine when there is no discernible stimulus for release of antidiuretic hormone (1).

The following criteria should be fulfilled before a diagnosis of SIADH can be made:

• persistent excretion of concentrated urine with no reason for ADH release
• normal renal and adrenal function
• no oedema or hypovolaemia should be present

Reference:

• (1) Hoorn EJ, van der Lubbe N, Zietse R. SIADH and hyponatraemia: why does it matter? NDT Plus. 2009;2(Suppl_3):iii5-iii11