nephrotic syndrome and hyperlipidaemia

Last reviewed 07/2021

• if creatinine clearance is relatively normal then proteinuria is associated with increased levels of LDL cholesterol (often the level of LDL cholesterol increase is inversely proportional to the reduction in serum albumin)
• hypertriglyceridaemia is unusual in nephrotic syndrome. If there is chronic renal failure then lipoprotein lipase activity is reduced and this can result in increased triglyceride levels
• HDL cholesterol - levels are normal or reduced