factors contributing to hyperhomocysteinaemia

Last reviewed 01/2018

  • male sex
  • increasing age
  • genetic defects in homocysteine metabolism
  • vitamin deficiencies
  • smoking
  • low physical activity levels
  • renal disease
  • hypothyroidism
  • drugs (theophylline, methotrexate, corticosteroids, cyclosporin, fibrates, phenytoin)

Reference:

  1. Br J Cardiol 2003;10:118-22.