epidemiology of gastrinoma

Last reviewed 07/2021

• gastrinomas are the most common islet cell tumours
• approximaely 45% of gastrinomas originate in the pancreas, but as many as 35–40% originate in the duodenum and about 10–15% primarily in peripancreatic lymph nodes
• gastrinomas can also occur in the stomach, lung, liver and ovary
• in approximately 25% of patients, the gastrinoma is part of MEN-I (in MEN-I, the gastrin-producing tumour is then often found in the duodenum)

Reference:

1. de Herder WW and Lamberts SWJ. Best Practice & Research Clinical Endocrinology & Metabolism; Volume 18(4): 477-495.