comparison of onset and duration of action of different phosphodiesterase (PDE5) inhibitors

Last reviewed 01/2018

 onset of action duration of action (hours)doses
sildenafil 20-30 minutes; peak action 60 minutes4-625-50-100mg
tadalafil60-120 minutes; peak action 120 minutes36-4810-20mg
vardenafil20-30 minutes; peak action 60 minutes4-65-10-20 mg

 

The respective summary of products must be consulted before prescribing any of the drugs mentioned.

Reference:

  1. British Heart Foundation (factfile 6/2005).Drugs and Erectile Dysfunction.