crossover study
Last reviewed 03/2021
Crossover study
- a type of controlled trial in which each subject acts as his own control, by receiving intervention "A" for one period of time and intervention "B" for another
- design is only appropriate for evaluating palliative treatments of chronic stable conditions
- bias can result based
on the order in which interventions A and B are received and the time interval
between receiving the interventions
- therefore to reduce these effects:
- there should be an adequate washout period between treatments;
- the groups should be split into two so that one group receives intervention A first and the other group receives intervention B first
- therefore to reduce these effects:
Reference:
- MeReC Briefing (2005);30 (supplement):1-7.