intercalated deficiency

Last reviewed 01/2018

An intercalary or intersegmental defect is a form of congential limb anomaly with failure of formation of parts. It is more widely known as phocomelia. A segment of a limb is absent with relatively normal segment distally. Examples include:

  • complete: the hand attaches to the trunk eg at the glenohumeral joint
  • proximal: forearm attaches to trunk
  • distal: hand attaches to humerus

Phocomelia is associated with the ingestion of thalidomide in pregnancy. It is also part of the Cornelia de Lange association.

Treatment is non-surgical with the introduction of a prosthesis.