classification of congenital hypothyroidism
Last reviewed 01/2018
Congenital hypothyroidism can be divided into:
- permanent congenital hypothyroidism - there is continuous deficiency of
thyroid hormone and requires treatment throughout life, can be further divided
into
- primary hypothyroidism - results from thyroid gland development (dysgenesis) or a disorder of thyroid hormone biosynthesis (dyshormonogenesis)
- secondary or central hypothyroidism - deficiency of thyroid stimulating
hormone (TSH)
- peripheral hypothyroidism - due to defects of thyroid hormone transport,
metabolism, or action
- syndromic hypothyroidism - congenital hypothyroidism is associated with
abnormalities of other organ systems
- transient congenital hypothyroidism - temporary deficiency which recovers during the first few months or years of life (1)
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