diagnosis of premature ovarian insufficiency

Last reviewed 01/2018

Diagnosing premature ovarian insuffificiency

• take into account the woman's clinical history (for example, previous medical or surgical treatment) and family history when diagnosing premature ovarian insufficiency
  
  
• diagnose premature ovarian insufficiency in women aged under 40 years based on:
  • menopausal symptoms, including no or infrequent periods (taking into account whether the woman has a uterus) and
  • elevated FSH levels on 2 blood samples taken 4-6 weeks apart
    
    
• do not diagnose premature ovarian insufficiency on the basis of a single blood test
• do not routinely use anti-Müllerian hormone testing to diagnose premature ovarian insufficiency

If there is doubt about the diagnosis of premature ovarian insufficiency, refer the woman to a specialist with expertise in menopause or reproductive medicine

Reference:

• NICE (November 2015). Menopause: diagnosis and management