host and viral risk factors associated with progression of chronic hepatitis B
Last edited 06/2018 and last reviewed 03/2022
host and viral risk factors associated with progression of chronic hepatitis
B
factors
|
host
|
viral
|
non modifiable
|
- male gender
- older age
- family history of HCC
- host genetic polymorphism
|
- unrelenting HBeAg-seropositive hepatitis
- sustained elevation in serum HBV DNA
- sustained elevation in serum ALT
- HBV genotypes C and D
|
modifiable
|
- excess alcohol intake
- obesity/NAFLD
- drugs (immunosuppressive/hepatotoxic)
|
- coinfection with HIV
- coinfection with HCV and HDV
|
Reference:
Related pages:
hepatitis B virus hepatitis