coffee consumption and prostate cancer
Last edited 01/2021 and last reviewed 03/2023
Coffee consumption has been reported to be inversely associated with prostate cancer risk and progression to advanced disease and mortality (1,2,3).
How could coffee be protective?
- protective effect is biologically plausible, given coffee's abundance of compounds with anti-oxidant and anti-inflammatory effects and reported effects on insulin levels (4,5)
Reference:
- Cao S, Liu L, Yin X, et al Coffee consumption and risk of prostate cancer: a meta-analysis of prospective cohort studies. Carcinogenesis 2014;35:256-61.
- Lu Y, Zhai L, Zeng J, et al Coffee consumption and prostate cancer risk: an updated meta-analysis. Cancer Causes Control 2014;25:591-604.
- Bosire C, Stampfer MJ, Subar AF, et al Coffee consumption and the risk of overall and fatal prostate cancer in the NIH-AARP Diet and Health Study. Cancer Causes Control 2013;24:1527-34.
- Tunnicliffe JM, Shearer J. Coffee, glucose homeostasis, and insulin resistance: physiological mechanisms and mediators. Appl Physiol Nutr Metab 2008;33:1290-300.