rhabdomyolysis and fluvoxamine

Last edited 12/2022 and last reviewed 12/2022

Rhabdomyolysis and fluvoxamine

Myalgia is a rare side effect of fluvoxamine (1).

A case report (1) describes rhabdomyolysis due to fluvoxamine monotherapy for obsessive-compulsive disorder

• a young adolescent developed pain in the extremities, and an increase in serum creatine kinase (CK) and myoglobin during fluvoxamine treatment
• adverse reactions were reversed immediately after the medicine was changed to another SSRI - sertraline

Reference:

• Zhang F, Gong W, Cui Z, et al. Rhabdomyolysis in a male adolescent associated with monotherapy of fluvoxamine. European Journal of Hospital Pharmacy Published Online First: 02 December 2022. doi: 10.1136/ejhpharm-2022-00353