progressive muscular atrophy
Last reviewed 01/2018
This is a form of motor neurone disease (MND).
Progressive muscular atrophy results from a lesion of anterior horn cells. The presentation is with asymmetrical limb wasting and weakness progressing to a condition where lower motor neurone signs predominate.
PMA accounts for 15-35% of cases of MND (1).
Reference:
- NICE (April 2006). Review decision on the use of Riluzole for the treatment of motor neurone disease.
clinical features of progressive muscular atrophy