acute vs. non-acute porphyria
Last reviewed 03/2022
The acute porphyrias include:
- acue intermittent porphyria
- hereditary coproporphyria
- variegate porphyria
Non-acute porphyrias include:
- porphyria cutanea tarda
- congenital porphyria
- erythropoietic protoporphyria
The accumulation of delta-aminolevulinate and porphobilinogen in acute porphyrias results in the characteristic abdominal pain and neuropsychiatric features.
Accumulation of specific uro- and coproporphyrins in the abscence of porphobilinogen excess results in the features of non-acute porphyria, particularly photosensitivity.