macrocytic anaemia with normoblastic marrow

Last reviewed 01/2018

Macrocytic anaemia with a normoblastic bone marrow presents as round macrocytes on the blood film.

Possible causes include:

  • alcohol
  • liver cirrhosis
  • reticulocytosis
  • marrow infiltration
  • hypothyroidism / myxoedema
  • myleloproliferative disease
  • myelodysplastic syndrome
  • acquired sideroblastic anaemia