clinical features
Last reviewed 06/2023
Clinical features include:
- non-thrombocytopenic purpura:
- over the extensor surface of the buttocks and legs
- rash is common and is often the presenting feature
- other skin manifestations:
- macules or papules
- urticaria especially of the face and legs
- lesions occur in crops and may be precipitated by abrading the skin
- arthritis:
- in up to two thirds of patients
- affects large joints, flitting in nature
- usually lasts only a few days
- nephritis - mild focal segmental glomerulonephritis, proteinuria, microscopic haematuria
- abdominal pain:
- a common feature and may precede other symptoms
- there may be melaena
- localised oedema around orbits of eyes, backs of hands and feet
- testicular inflammation in males
- central nervous system involvement occurs rarely, and can result in fits and coma