features due to local effects

Last reviewed 01/2018

Where hypopituitarism has a neoplastic or infiltrative aetiology the following clinical features may be present:

  • headache
  • visual field defects:
    • most commonly a superior bi-temporal quadrantanopia
    • progressing to a bitemporal hemianopia
  • cerebrospinal fluid rhinorrhoea due to inferior extension of the tumour
  • III, IV and VI nerve palsies due to lateral extension of the tumour