asymptomatic raised uric acid and thiazides
Last reviewed 06/2022
- occurs in up to 30% of hypertensive patients treated with thiazide diuretics
- the presence of hyperuricaemia per se does not require withdrawal of the
thiazide or treatment
- if gout develops however then it is prudent to stop thiazide treatment
and initiate alternative therapy for hypertension
- if a patient has a history of gout then treatment with thiazides are best not used - if necessary concurrent treatment with allopurinol can allow continued treatment with a thiazide
Reference:
- (1) Prescriber (2001), 12 (18), 49-61.