U3 - RNP autoantibody
Last reviewed 01/2018
U3-RNP autoantibody
- target antigen - Fibrillarin
- occurs in 5% systemic sclerosis
- clinical association
- isolated pulmonary arterial hypertension
- cardiac involvement
- myositis and poor outcome in diffuse cutaneous systemic sclerosis
Reference:
- 1) Arthritis Research Campaign (2010). Topical Reviews - Systemic sclerosis and related disorders.