lipid-lowering drugs
Last reviewed 12/2022
There are classified as:
- exchange resins } for most patients replaced
- nicotinic acid and analogues} by statins as first line agents
- fibrates - effective at lowering triglyceride levels and increasing HDL-cholesterol, in addition to lowering LDL-cholesterol - generally also used as a second line treatment to statins
- HMG CoA reductase inhibitors (statins) - the most potent drugs for treating hypercholesterolaemia
- others
- e.g. fish-oil preparations rich in omega-3 marine triglycerides - useful in the treatment of severe hypertriglyceridaemia; however may sometimes aggravate hypercholesterolaemia
- e.g. agents such as ezetimibe, the first selective cholesterol absorption inhibitor, have been introduced then this means there are further options in the management of hyperlipidaemia
ispaghula as a lipid-lowering drug
fish oils as a lipid lowering drug
trials with respect to treatment of hypercholesterolaemia
lipid lowering treatment in primary prevention
lipid lowering treatment for secondary prevention
red rice as a lipid lowering treatment
proprotein convertase subtilisin/kexin type 9 serine protease (PCSK9) inhibitors