investigation

Last reviewed 01/2018

In practice a young patient with longstanding typical symptoms does not require investigation.

Investigation should be considered if the following features are present:

  • atypical symptoms
  • dysphagia
  • short duration of symptoms in patient over 55 yr
  • weight loss

The investigation of GORD consists of one, or a combination, of the following:

  • endoscopy:
    • the most common initial investigation
    • can exclude other causes or dysphagia such as carcinoma
    • is normal in up to 65% of cases
    • symptoms requiring urgent referral of patients for endoscopy are (1):
      • gastrointestinal bleeding
      • iron deficiency anaemia
      • progressive unintentional weight loss
      • progressive difficulty swallowing
      • persistent vomiting
      • epigastric mass on palpation
      • suspicious barium meal result or other suspicious imaging result
    • factors requiring consideration of referral of patients for endoscopy include (1) :
      • previous gastric ulcer
      • previous gastric surgery
      • non-steroidal anti-inflammatory drug use
      • pernicious anaemia
      • family history of gastric cancer
  • barium radiology:
    • may be used, particularly if a diagnosis of erosive oesophagitis is being considered
  • 24 hour oesophageal pH monitoring:
    • particularly useful if a link between symptoms and acid reflux needs establishing

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